The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe.

Exciting Opportunity at MSK: Associate Lab Director, Gene Editing & Screening Core Facility

Role Overview:

• As Associate Lab Director, you will balance scientific leadership with operational and financial oversight to ensure the GES Core Facility remains a pioneering, sustainable resource for MSK investigators.
• Partner with the Core Facility Director to define short-, medium-, and long-term scientific strategy aligned with MSK research priorities
• Lead and support functional genomics initiatives, including CRISPR and RNAi-based screening platforms
• Oversee development and optimization of advanced methods, assays, and screening technologies (HTS/HCS; live and fixed cell imaging)
• Provide scientific consultation to investigators and liaise with the broader scientific community
• Lead day-to-day operations, including workflow optimization, resource allocation, and service delivery
• Ensure financial stewardship by developing and leading budgets and meeting operational financial goals
• Lead hiring, training, mentoring, and career development of scientific staff
• Champion a culture of mentorship, performance excellence, and continuous improvement
• Represent MSK at external conferences and NCI/NIH-sponsored meetings

Key Qualifications:

• Ph.D. in Biology, Cell Biology, Biochemistry, Pharmacology, or a related discipline
• 5+ years of experience in academic, pharmaceutical, or biotechnology settings
• Deep expertise in CRISPR and RNAi technologies and their application to drug discovery and development
• Demonstrated experience with gene perturbation strategies, KI/KO cell line generation, viral production, and assay development
• Hands-on knowledge of chemical compound libraries, automated liquid handling, plate readers, and high-speed confocal imaging systems
• Experience developing and leading budgets in partnership with internal stakeholders
• Consistent record leading laboratory staff and overseeing complex laboratory operations
• Excellent written, verbal, and interpersonal communication skills

Core Skills:

• Strong multitasking, prioritization, and planning skills in a fast-paced research environment
• Strategic thinker who stays current with emerging technologies and field advancements
• Collaborative leader who builds strong relationships across teams and disciplines
• Passionate mentor committed to staff development and scientific growth
• Effective, adaptable communicator across diverse audiences and settings
• Results-oriented with the ability to perform under challenging conditions
• Precise and decisive bench scientist with strong problem-solving skills
• Flexible and agile, able to pivot quickly as scientific or operational needs evolve

Additional Information:

• Schedule: Monday - Friday 37.5 hrs, Onsite (may have the flexibility to work remotely once a week)
• Location: 417 E. 68th Street, NYC
• Reporting to: Core Director

Helpful Links:

Closing:

At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills.

MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.

Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.