Description:

The College of Pharmacy is looking for either a Researcher 1 or Researcher 2 to fill this role. 

Provides expertise in support of research projects in engineering, biology, mathematics, statistics, computer science, physics, etc. Prepares and edits research papers, proposal, and reports. Performs advanced testing procedures and analyses of data. May prepare samples for testing. Performs advanced testing procedure and performs analyses of data. Makes uses of a variety of specialized equipment typical within area of specialization. May contribute to grant proposal development.

1. Ensures experiments are performed according to specifications.
2. May make recommendations to changes in procedure, processes, or experimental design.
3. Understands and applies broad theoretical concepts. Develops understanding of specialized scientific or engineering field.
4. Develops leadership and management skills.
5. Assignments are difficult and broad requiring originality and ingenuity.
6. May be assisted by lower-level personnel. Supervision: Receives minimal supervision conferring with higher levels only in usual situations.

The Department of Pharmacological and Pharmaceutical Sciences (PPS)at the College of Pharmacy, University of Houston invites applications for a full-time Researcher Natural Science position in the areas of pharmaceutics and pharmacokinetics. The primary responsibility is to lead the day-to-day effort in conducting research in the lab as the researcher scientist for the research group; will participate in conducting experiment, sample collection and analysis, data analysis, prepare manuscripts, present at conferences, and participate in grant writing in the areas of LCMS analysis of disease biomarkers, proteinomics and metabolomics in preclinical and clinical samples.

The researcher scientist is expected to perform all duties described in the assigned projects, including skills but not limited to (1) develop LCMS global and targeted proteomic and metabolomic workflow for research projects in the lab, and involved in the set-up of high throughput quantitative proteomics/peptidomics platform* (2) Performed proteomics/peptidomics based technique for cancer biomarker discovery study by using multiplexing of Tandem Mass Tags labeling approach; (3) Conducted the proteome/peptidome differential profiling, including cell-surface, media, cytoplasm and nucleus from different cancer cell-lines; (4) Developed the matrix preparation for MALDI-TOF imaging analysis of tissue in preclinical and clinical settings; (5)train, supervise, and mentor graduate students, when required; (6)present research at national and international meetings.

*The major Mass spectrometry equipment installed in our facility (our platform):
1. MALDI Imaging mass spectrometry: Thermo Scientific™ Orbitrap Exploris™ 480 Mass Spectrometer with MALDI
2.Thermo Scientific™ Orbitrap Exploris™ 480 Mass Spectrometer with Vanquish Flex UHPLC System or Vanquish Neo UHPLC System
4. SCIEX Triple Quad™ 7500 LC-MS/MS System – QTRAP® Ready
5. SCIEX Triple Quad™ 5500 LC-MS/MS System – QTRAP® Ready (2 equipment)
6. Mass spectrometry (MS) techniques: electrospray ionization mass spectrometry (ESI-MS), atmospheric pressure chemical ionization mass spectrometry (APCI-MS) and matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS).


Experience will be considered in lieu of education.
Education will be considered in lieu of experience.

Researcher 1 MQ: Bachelor's Degree with 1 years experience.
Researcher 2 MQ: Bachelor's Degree with 3 years experience.

Qualifications:
Master degree with wet lab research experience in an academic or industry setting. Strong academic and research training directly related to High resolution MS and protein quantitative analysis and proteomic analysis are desirable. Experience in laboratory animal handling and experimentation.
Preferred Qualifications:
Master degree in medicine, pharmacy, or other relevant fields with 5 more years of proteinomics experience in an academic or industry setting.

All positions at the University of Houston-System are security sensitive and will require a criminal history check.

The University of Houston System and its universities are an Equal Opportunity Institution.