Department: Pharmacological & Pharmaceutic

Salary: 49,400-56,200

Description:

Works under the direction of a faculty member. Provides expertise in the design, operation and analysis of experiments or research projects in areas such as chemistry, biology, psychology, sociology, mathematics, statistics, computer science, physics, optometry, all fields of engineering, etc. May prepare samples for testing. Performs advanced testing procedures and performs analyses of data. Prepares reports. Makes uses of a variety of specialized equipment typical within area of specialization. May contribute to grant proposal development.

1. Ensures experiments or research efforts are performed according to specifications.
2. May make recommendations to changes in procedures, processes, or experimental design.
3. May prepare and/or edit research papers, proposals and reports.
4. Possesses, understands, and applies an advanced knowledge crossing fields of specialization to develop unique and new approaches or ideas.
5. Understands and uses effective management techniques.
6. Designs, operates and analyzes multiple large and/or complex experiments or research projects.
7. Reviews progress of projects. May serve as liaison with other areas of specialization to obtain support or technical expertise for projects.
8. Defines procedures or processes to be used in the research investigations.
9. May personally conduct important and/or technically complex investigations.
10. Operates with wide latitude for unreviewed action subject only to institutional policies and guidelines and ethical considerations.
11. Provides direction and supervision of graduate and undergraduate research assistants involved in experiments or research.

MQ: Ph.D. Degree with 3 years of experience.

Additional Posting Information:
Researcher 2 Nat Science - Pharmaceutics and Pharmacokinetics

Additional Posting Information:
The Department of Pharmacological and Pharmaceutical Sciences (PPS)at the College of Pharmacy, University of Houston invites applications for a full-time Researcher Natural Science position in the areas of pharmaceutics and pharmacokinetics. The primary responsibility is to lead the day-to-day effort in conducting research in the lab as the researcher scientist for the research group; will participate in conducting experiment, sample collection and analysis, data analysis, prepare manuscripts, present at conferences, and participate in grant writing in the areas of LCMS analysis of disease biomarkers, proteinomics and metabolomics in preclinical and clinical samples.
The researcher scientist is expected to perform all duties described in the assigned projects, including skills but not limited to (1) develop LCMS global and targeted proteomic and metabolomic workflow for research projects in the lab, and involved in the set-up of high throughput quantitative proteomics/peptidomics platform* (2) Performed proteomics/peptidomics based technique for cancer biomarker discovery study by using multiplexing of Tandem Mass Tags labeling approach; (3) Conducted the proteome/peptidome differential profiling, including cell-surface, media, cytoplasm and nucleus from different cancer cell-lines; (4) Developed the matrix preparation for MALDI-TOF imaging analysis of tissue in preclinical and clinical settings; (5)train, supervise, and mentor graduate students, when required; (6)present research at national and international meetings.

*The major Mass spectrometry equipment installed in our facility (our platform):
1. MALDI Imaging mass spectrometry: Thermo Scientific™ Orbitrap Exploris™ 480 Mass Spectrometer with MALDI
2.Thermo Scientific™ Orbitrap Exploris™ 480 Mass Spectrometer with Vanquish Flex UHPLC System or Vanquish Neo UHPLC System
4. SCIEX Triple Quad™ 7500 LC-MS/MS System – QTRAP® Ready
5. SCIEX Triple Quad™ 5500 LC-MS/MS System – QTRAP® Ready (2 equipment)
6. Mass spectrometry (MS) techniques: electrospray ionization mass spectrometry (ESI-MS), atmospheric pressure chemical ionization mass spectrometry (APCI-MS) and matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS).

Qualifications:
Master degree with wet lab research experience in an academic or industry setting. Strong academic and research training directly related to High resolution MS and protein quantitative analysis and proteomic analysis are desirable. Experience in laboratory animal handling and experimentation.
Preferred Qualifications:
Master degree in medicine, pharmacy, or other relevant fields with 5 more years of proteinomics experience in an academic or industry setting.

Required Attachments by Candidate
Curriculum Vitae, Cover Letter/Letter of Application, Research Statement. Letters of Recommendation upon request.