This position will remain open until a successful candidate has been identified.
UCSD Layoff from Career Appointment: Apply by 09/08/2023 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 09/19/2023. Eligible Special Selection clients should contact their Disability Counselor for assistance.
The Moores Cancer Center is one of just 53 NCI-designated Comprehensive Cancer Centers in the United States and the only one in San Diego County. As a consortium cancer center, it is a collaborative partnership between the UCSD: encompassing 14 departments (12 clinical, 2 basic sciences), 3 professional schools (School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, School of Public Health), UCSD Health oncology hospitals and clinics; the basic and public health research and outreach of San Diego State University, and the basic and translational research of the La Jolla Institute of Immunology.
These various programs and units are all dedicated to fulfilling the Moores Cancer Center's mission of reducing cancer's burden. As such, it ranks among the top centers in the nation conducting the continuum of cancer research, providing advanced patient care, and serving the community through outreach and education programs. As a top-ranking, future-oriented organization, we offer challenging career opportunities in a fast-paced and innovative environment. Moores Cancer Center follows a progressive philosophy of career-path development for its employees including opportunities for cross-training, professional development, and progressive responsibility.
MCC's mission is to transform cancer care in our catchment area and beyond by driving exceptional scientific discoveries, and innovations in prevention, detection, care, and training. MCC will make a global impact on improving health by reducing cancer burden through accelerated discovery and translation, compassionate and interdisciplinary care, education and community engagement, with the foundation of our core values - Excellence, Innovation and Risk-Taking, Collaboration, Diversity and Service.
Under supervision in a hematology/oncology research lab, assist with performing research studies and troubleshooting new and established assay techniques. Assist with performing and analyzing in vivo and in vitro experiments to study expression of specific proteins in ovarian, breast, and lung cancer and to define the role of specific proteins in promoting tumor growth, metastasis, and tumor initiation using primary cancer cells and cell lines. Assist with conducting in vivo experiments with patient-derived xenograft mouse models to assess treatment effects with novel agents. Assist with processing and banking primary human and mouse tumor samples. Other duties assigned as needed.
Theoretical knowledge of immunology, molecular biology, cell biology, and protein chemistry.
Ability to perform standard molecular biology techniques, including PCR, SDS Page electrophoresis, western blotting, ELISA assays, and recombinant DNA manipulation.
Ability to culture primary tumor cells.
Knowledge of various mice handling techniques.
Ability to establish patient-derived xenograft (PDX) including subcutaneous injection model and orthotopic mice model.
Ability to perform formulation of different therapies and conduct animal dosing (IV, PO, IP, SC), tumor implantation, blood/tissue collection from mice, tumor measurements, tumor freezing and formalin-fixing procedures.
Knowledge and willingness to handle blood, plasma and other human specimens for processing and shipping. Must be willing and able to work with human samples, animals, biohazardous materials and radioactivity.
Excellent organizational skills to order and maintain lab equipment and order supplies.
Ability to follow UCSD Safety and Hazardous Materials guidelines. Ability and willingness to work with hazardous/biohazardous materials.
Knowledge of various cell-based assays pertaining to investigating cancer stem cell hypothesis.
Effective interpersonal and oral communication skills. Skill to effectively and clearly communicate with tact, diplomacy, discretion, and flexibility to faculty, academicians, students, and staff including those of diverse ethnicity, culture, and foreign nationals. Ability to present information clearly and concisely.
Knowledge of the cancer stem cell hypothesis and markers, particularly as it pertains to breast cancer.
UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 8 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom - life is their laboratory. UC San Diego's rich academic portfolio includes six undergraduate colleges, five academic divisions and five graduate and professional schools. The university's award-winning scholars are experts at the forefront of their fields with an impressive track record for achieving scientific, medical and technological breakthroughs.