Current UC San Diego employees who apply by 5/30/2023 will have priority consideration for this position. Recruiters will refer qualified internal candidates after the first 7 days of the job posting. All qualified external applicants and additional internal applicants who apply after the priority date may have further consideration pending the results of the initial review.

DESCRIPTION

UCSD Health Sciences is a $1 billion dollar plus organization encompassing 16 academic departments (14 clinical, 2 basic sciences), 2 preacademic/hospital departments, 2 professional schools (School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences), 2 hospitals, and various other programs and units all dedicated towards fulfilling the Health Sciences missions. The UCSD Department of Cellular and Molecular Medicine (CMM) is one of two basic science units in the School of Medicine where world-class researchers study fundamental cellular processes and pathways using a variety of techniques from classical genetics and fluorescence microscopy to high throughput genomics, systems biology, and crystallography. Our 36 faculty and over 200 postdoctoral scholars, graduate students, and research staff work on the cutting edge of biology, cutting across fields from basic biochemistry and genetics to genomics, systems biology and stem cell biology. The faculty also play a major role in medical and graduate student training, providing educational and programmatic offerings that span several disciplines and provide diversity to meet the interests of a broad spectrum of students and scholars. The diverse mix of ages, backgrounds, and talents creates a robust work environment with challenging career opportunities and a commitment to continued growth potential. We constantly seek to recruit highly motivated, technologically advanced, and deeply interested individuals who are ready to become a part of our dynamic research and educational environment.

Under direction, the Structural Biology Research Associate will work independently to design, develop and perform advanced laboratory experiments related to the cloning, expression, purification, and biochemical/structural characterization of proteins and protein complexes important for mitotic and meiotic genome organization and cell division. The Research Associate will make innovative, original contributions to experimental techniques as part of method development and achieve the goals within a defined time frame.

As a senior member of the research team, the incumbent will also be responsible for teaching and guidance of undergraduate students, graduate students, and starting post-doctoral fellows. Performs other duties as assigned.

MINIMUM QUALIFICATIONS

• Advanced theoretical knowledge of and direct experience with chemistry and biology typically acquired at the university level or an equivalent level of education and experience.

• Proven advanced knowledge of structural biology; specifically x-ray crystallography and electron microscopy.

• Demonstrated experience in chemistry procedures and chromatography including chromatographic separations, spectrophotometry, proper handling of enzymes; proven ability to perform enzymatic reactions.

• Proven ability to develop, design, and execute research involving complex proteins and protein-DNA interactions.

• Proven ability to perform protein purifications using FPLC instruments.

• Proven ability to calculate and prepare chemical solutions accurately, ability to carry out new experimental procedures with accuracy and efficiency.

• Proven ability to follow stepwise experimental protocols, skill and ability to keep accurate data.

• Proven ability to provide significant innovative contributions to laboratory experiments and procedures.

• Demonstrated experience providing training to lab members (Postdocs, students, staff researchers) related to protein purification and biochemical analysis.

• Strong interpersonal communication skills; experience setting priorities and learning new techniques; experience setting up techniques following published protocols; experience training, orienting and providing direction to new users to lab operating procedures and routine methods.

• Demonstrated experience managing daily operations of a medium- to large-sized laboratory.

• Previous experience working with biohazardous materials and potential carcinogen

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  About University of California San Diego

  UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 8 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom - life is their laboratory. UC San Diego's rich academic portfolio includes six undergraduate colleges, five academic divisions and five graduate and professional schools. The university's award-winning scholars are experts at the forefront of their fields with an impressive track record for achieving scientific, medical and technological breakthroughs.

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