Associate or Full Specialist/Scientist | Small Molecule Discovery Center
University of California San Francisco
Location: San Francisco, California
Internal Number: JPF04526
Associate or Full Specialist/Scientist Small Molecule Discovery Center
Department of Pharmaceutical Chemistry University of California, San Francisco
The Small Molecule Discovery Center (SMDC) at UCSF is seeking a highly collaborative biologist or biochemist with a passion for drug discovery and chemical biology. The successful applicant will design, optimize and conduct fragment-based, biochemical, and cell-based high-throughput screens, analyze and upload screening data, train users, and assist with compound library management. Scientists who enjoy working on diverse problems and thrive in a team-oriented, multi-disciplinary environment are ideally suited for this position.
The SMDC is a leader in academic drug discovery and chemical biology. When biomedical research at UCSF uncovers new potential targets for drug discovery, the SMDC works with researchers to develop chemical tools and drug leads to further understand and exploit these targets for human health. Current major projects include antiviral drug discovery, integration of experiment and machine-learning models, and developing covalent drug discovery for challenging and novel targets.
Lead and run high-throughput screening projects in collaboration with the initiating labs
Develop and optimize screening assays
Execute automated screening campaigns
Learn/develop new technologies to address important problems in drug discovery and chemical biology
Work with project teams, informatics specialist, and medicinal chemistry scientists to validate and advance chemical matter
Train users on SMDC equipment and assay technologies
Perform other professional duties as needed
Associate Specialist: Master's degree (or equivalent degree) or five to ten years of experience in screening and drug discovery.
Full Specialist: PhD or related terminal degree in Chemistry, Pharmacology, Biology, or related discipline; or ten or more years of experience in screening and drug discovery
Experience with high-throughput screening, fragment screening, and/or cell biology
Enthusiasm for working in a team research environment
Strong written and communication skills
Candidates must meet the required qualifications at the time of appointment.
Candidate's CV must state required qualifications (or if pending) upon submission.
PhD or related terminal degree in Chemistry, Pharmacology, Biology, or related discipline
Experience with liquid handling equipment, high-content imaging and analysis software
Experience in biochemical and cell-based assay development
Experience with biophysical methodology, such as DSF, SPR
Experience with HTS data management/visualization software (Dotmatics, Vortex, Datawarrior, Knime)
Salary will be commensurate with the applicant's experience and training.
Applicants should submit a brief cover letter and a curriculum vitae. Please apply online and submit these documents along with the contact information for at least two references to: https://aprecruit.ucsf.edu/JPF04526.
See Table 24B for the salary range for this position. A reasonable estimate for this position is $67,400-$173,900.
Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).
As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.
UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.