Department: COP Drug Discovery and Biomedical Sciences
Advertised Salary Range: $45,000 -$50,000
Advertised Job Summary:
The Zhu lab in the Department of Drug Discovery and Biomedical Sciences at the College of Pharmacy, University of South Carolina, is seeking an accomplished and motivated Postdoctoral Fellow to work on ongoing R01 project funded by the National Institute of Drug Abuse. The R01 project aims at elucidation of the molecular, cellular and behavioral mechanisms underlying HIV-1 regulatory protein, transactivator of transcription (Tat) protein-mediated dysregulation of dopaminergic neurotransmission through the monoamine transporters and its associated cognitive deficits in concurrent cocaine or methamphetamine abusers. The multidisciplinary approaches include studies using cell culture (cells expressing human dopamine transporter, human norepinephrine transporter, and their mutants), radioligand uptake/binding, Co-IP and GST pull-down assays, cell surface biotinylation, transporter-mediated uptake and release, transgenic HIV-1 Tat transgenic mouse model, single residue on dopamine transporter knock in mouse model and behavioral testing.
Additional information about Zhu's laboratory is available at: http://www.sc.edu/study/colleges_schools/pharmacy/faculty-staff/zhu_jun.php
Advertised Minimum Qualifications :
Successful candidates should have a Ph.D. in Neuroscience, neuropharmacology, behavior pharmacology or related discipline. Candidates with training or experience in regulation of membrane transporter function and expression are encouraged to apply.
The University of South Carolina is a globally recognized, high-impact research university committed to a superior student experience and dedicated to innovation in learning, research and community engagement. Founded in 1801, the university offers more than 300 degree programs and is a top-tier Carnegie Foundation research institution. More than 50,000 students are enrolled at one of 20 locations throughout the state, including the research campus in Columbia. With 60 nationally ranked academic programs including top-ranked programs in international business, the nation's best honors college and distinguished programs in engineering, law, medicine, public health and the arts, the university is helping to build healthier, more educated communities in South Carolina and around the world.