Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
This position is full-time and works approximately 40 hours per week.
Department Name/Job Location:
This position is in the Department of Neurology. This position is for the Medical School Campus.
This position is in the Biomarker Core Lab for the Dominantly Inherited Alzheimer Network Trials Unit (DIAN TU), the first clinical trial for the prevention of Alzheimer’s dementia in families with disease-causing mutations. The Staff Scientist assists in developing and conducting clinical research projects, including experimental design, data analysis and documentation of experimental results.
PRIMARY DUTIES AND RESPONSIBILITIES:
Following instructions and discussions with principal investigator, develops and maintains clinical research laboratory standard operating procedures (SOPs), work instructions, and operational workflows for all clinical trial research operations within the DIAN-TU Biomarker Core lab.
Performs fluid biomarker assays and the quality control and data analysis of the assays in accordance with laboratory SOPs and ICH-GCP standards. Assesses new technology platforms for suitability for the clinical trial analyses.
Processes fluid biomarker samples and manages the sample and data distribution flows among the Biomarker Core lab, the clinical trial contract research organizations (CROs), and the pharmaceutical referral labs.
Implements and ensures compliance with all applicable clinical trial regulatory standards (ICH-GCP; GLP) and established safety, regulatory, and HIPPA procedures.
Documents research topics and prepares and submits papers based on research work for publications and presentations to committees and scientific peers.
Solves practical problems relating to difficulties with equipment or test subjects. Suggests technical or procedural improvements in testing methods. Collaborates with other internal and external functional groups where necessary to support milestone achievements and to manage study issues and obstacles.
Conducts literature searches related to research project.
Participates in the project management of assigned studies.
Master’s degree with four years of experience in research lab operations or an equivalent combination of education and experience equaling nine years.
Applicant Special Instructions:
This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment.
Experience with performing immunoassays.
ICH Method validation experience.
Experience in GxP (GLP, GCP, GMP) environment and implementation of continuous improvement practices.
Excellent organizational skills with a high attention to detail.
Ability to prioritize tasks in a diverse environment.
Ability to communicate well in oral and written form with all levels of personnel.
Analytical, reasoning and problem-solving skills.
Ability to analyze and interpret statistical data and to communicate data in a clear, concise manner.
Computer literacy, including the ability to use a variety of software packages to analyze data.
The hiring range for this position is $46,779 - $63,170 annually.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.