Principal Duties and Responsibilities:

70%  Metabolomics/adductomics experiments to identify endogenous and exogenous sources of DNA adducts
Extract DNA from cells and tissues, grow human cells in the presence of isotopically labeled metabolites, detect labeled metabolites and DNA adducts using Orbitrap mass spectrometry, perform biochemical assays.

15%  Preparation of manuscripts, funding applications, reports, presentations, maintain research notebook and SOPs
Prepare reports, research papers, etc., describing research results,

10%   Mass spectrometry analysis of DNA adducts and metabolites
Operate mass spectrometry equipment to analyze DNA adducts and metabolites

5%   Supervise graduate research assistants and undergraduates
Teach basic laboratory techniques, maintain safety

Supervision:

Help direct experiments of several research assistants
 

Required Qualifications:
Ph.D. in Chemistry or Medicinal Chemistry and prior experience with mass spectrometry of DNA modifications

Preferred Qualifications:
Experience with mass spectrometry, human cell culture, adductomics, metabolomics

Working Conditions:
The majority of work will be conducted in a laboratory setting.