The Wyss Institute for Biologically Inspired Engineering seeks a creative and talented individual to join our team as a Scientist I to advance preclinical testing and modeling of the human immune system using organ-on-chip technology.
This candidate will contribute to research programs in collaboration with industry partners or funded by philanthropic agencies. Current programs use the human lymph node chip and other immune models to identify effective vaccines and adjuvants. Further, the candidate will initiate and develop projects in immuno-oncology, for example, the study of immunosuppression in cancer and CAR-T cell trafficking.
The candidate will independently develop and conduct scientific studies in support of platform/project goals using microfluidic Organ on Chip primary cell culture, attenuated vaccine strains of viral pathogens, adjuvants and various in-vitro cell based assays. These may include well-known techniques like qPCR/TaqMan, ELISA, western blots, enzymatic assays, imaging, and flow cytometry. The candidate is expected to deploy new assays and techniques from their experience or get training in novel approaches. They are expected to work independently with minimal guidance from academic staff to design experiments, learn new skills, troubleshoot, and to contribute intellectually to the project. They will develop creative solutions for scientific key questions related to using these immune models. In addition, the candidate will perform lab management activities including but not limited to inventory management, ordering equipment etc. Further, they will guide research assistants and trainees in setting timelines, acquiring and maintaining inventory, designing and interpreting experiments. The candidate will present data and conclusions at meetings within the Wyss Institute. The candidate is expected to contribute significantly to the authoring of manuscripts and patent applications.
This is a one year term position with the possibility of renewal.
The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the way nature builds. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances and launching startup companies. For more information, visit: http://wyss.harvard.edu/.
Harvard offers an outstanding benefits package including:
Time Off: 3 - 4 weeks paid vacation, paid holiday break, 12 paid sick days, 11.5 paid holidays, and 3 paid personal days per year.
Medical/Dental/Vision: We offer a variety of excellent medical plans, dental & vision plans, all coverage begins as of your start date.
Retirement: University-funded retirement plan contributions from 5% to 15% of eligible compensation, based on age and earnings with full vesting after 3 years of service.
Tuition Assistance Program: Competitive tuition assistance program, $40 per class at the Harvard Extension School and discounted options through participating Harvard grad schools.
Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
Wellness options: Harvard offers programs and classes at little or no cost, including stress management, massages, nutrition, meditation and complimentary health services.
Harvard access to athletic facilities, libraries, campus events and many discounts throughout metro Boston.
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Salary Grade: 056
Union: 00 - Non Union, Exempt or Temporary
Bachelor's degree in cell biology or Bioengineering with at least four years of experience involving aseptic primary human cell culture and biology techniques, such as ELISA, qPCR, microscopy or related experience required. Advanced education may count towards years or experience.
Master's degree in Cell Biology or Bioengineering preferred. Candidates with experience in multiple primary cell types, specifically in human immune cell culture, will be strongly considered. Immunology experience preferred. Work experience in pharmaceutical or medical device companies will be a significant addition and will be strongly considered. Experience with cell culture in microfluidic device/three dimensional cell culture/bioprinting is a plus. Ability to work well independently and to collaborate with a multidisciplinary group is essential. The candidate should be proficient with personal computers and applicable software packages (Microsoft Office). Additional experience in analysis software such as Prism, R, Imaris is a plus. Good written and oral communication skills are essential. The candidate should be highly motivated, detail-oriented, organized, and able to take initiative. Experience in preparation of technical reports, journal articles and presentations.
EQUAL OPPORTUNITY EMPLOYER: We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Internal Number: 52621BR
About Harvard University Medical School
Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders in many disciplines who make a difference globally. The University, which is based in Cambridge and Boston, Massachusetts, has an enrollment of over 20,000 degree candidates, including undergraduate, graduate, and professional students. Harvard has more than 360,000 alumni around the world. The University has twelve degree-granting Schools in addition to the Radcliffe Institute for Advanced Study, offering a truly global education. Established in 1636, Harvard is the oldest institution of higher education in the United States.